Filippo Sassetti

 

Goa, India 1509

Later distinguished as a renowned glassmaker and alchemist, Antonio Neri was born into a patrician household. In the Florentine baptism records, his entry was made on a Thursday, the first of March, 1576. He was born the previous evening, to Dianora Parenti and Neri Neri. His godmother is listed in the document as Ginevra Sassetti. Not a great amount is known about her; she was from a prominent family, at the time in her late fifties. However, there are indications that other members of her family interacted with the Neri's. Her nephew Filippo mentions Antonio's father favorably several times in letters, providing a fascinating glimpse into the way disease was diagnosed and treated.

When Antonio was born, his father Neri Neri was in his early thirties, and already a highly regarded physician. Baccio Valori was director of the famed Laurentian Library in Florence and steward of the Medici's simples (medicinal herbs) garden. He was friend to Neri Neri and godfather to Antonio's oldest sister Lessandra. Between 1583 and 1588, Valori received letters from a mutual friend, Filippo Sassetti, who was living in Goa and Cochin – trading settlements in India. Filippo was a native Florentine; he attended university in Pisa with Valori and they became lifelong friends. After Sassetti's father was forced to sell the family home to pay off a debt. Filippo moved to Lisbon and became a spice trader. Not suited for a desk job, he soon set sail seeking adventure in the orient. 

In a 1586 letter to his old friend Valori, Sassetti discusses an Indian remedy against the plague, with a substance called bezoar. The bezoar stone is a mass that develops and becomes trapped in the digestive systems of certain animals. It often resembles a smooth rock. Some thought ground bezoar to be a universal antidote to any poison. Sassetti was puzzled about how the grindings of bezoar could work to cure the plague. Its Aristotelian elemental properties would not be a match for correcting the imbalance of humors in the body. "This is a principle," he explains, taught to him by Neri Neri. "I have thought about it and I can not understand how it works, because the plague is of the same corruption and this is a lack of heat inherent in the humidity. And the stones, if I recall correctly, they have a cold and dry complexion, hence may not precede the restoration of heat. Messer Neri one time did me the favor of telling me." 

In another letter to Baccio Valori, Sassetti notes that he has collected rare varieties of cinnamon in his travels along the Malibar coast in India. His intention was to rediscover the species thought to be a powerful cure of disease by the ancients. He planned to send a parcel of seeds of these and other medicinal plants. "If it pleases God, in the coming year, I will send this to you, so that you may see it all, together with our Messer Neri Neri, who graces my memories." Later he writes that he is sending Baccio the discourse on cinnamon, which he has compiled, along with some plants. These, it later turned out, were water damaged in the journey. He had hoped for some help from Neri Neri on the question of whether the cinnamon he collected from the island of Zeilan [Ceylon], is the same thing as the curative cinnamon of Mantua described by the ancients. Valori was an authority on these matters in his own right. As librarian for the Medici's imposing collection of books and manuscripts, he had vast academic access. As keeper of the simples garden, he had first hand experience in horticulture and its derivative medicinal cures. 

The principles of "humorism" were passed down from celebrated physicians of the ancient world, like Galen, Hippocrates and Dioscorides. It was thought that the cure of disease was dependent on the restoration of balance between four substances in the body: blood, phlegm, black bile and yellow bile. In turn, each of these was associated with one of the Aristotelian elements: air, water, earth and fire respectively. Each was further associated with specific symptoms and characteristic traits of the patient, even their psychological outlook and physical complexion. This system formed the foundation of Western medicine and was taught and practiced well into the nineteenth century. Although, within Antonio Neri's lifetime newer experimentally based methods did start to take hold. A decade after his father's death, in a 1609 letter, Antonio boasts about his success in curing disease in Antwerp using the methods of the medical upstart Paracelsus. It is unlikely that his father would have approved.

*This post first appeared here 13 August 2014.

Filippo Sassetti

Goa, India 1509

Later distinguished as a renowned glassmaker and alchemist, Antonio Neri was born into a patrician household. In the Florentine baptism records, his entry was made on a Thursday, the first of March, 1576. He was born the previous evening, to Dianora Parenti and Neri Neri. His godmother is listed in the document as Ginevra Sassetti. Not a great amount is known about her; she was from a prominent family, at the time in her late fifties. However, there are indications that other members of her family interacted with the Neri's. Her nephew Filippo mentions Antonio's father favorably several times in letters, providing a fascinating glimpse into the way disease was diagnosed and treated.

When Antonio was born, his father Neri Neri was in his early thirties, and already a highly regarded physician. Baccio Valori was director of the famed Laurentian Library in Florence and steward of the Medici's simples (medicinal herbs) garden. He was friend to Neri Neri and godfather to Antonio's oldest sister Lessandra. Between 1583 and 1588, Valori received letters from a mutual friend, Filippo Sassetti, who was living in Goa and Cochin – trading settlements in India. Filippo was a native Florentine; he attended university in Pisa with Valori and they became lifelong friends. After Sassetti's father was forced to sell the family home to pay off a debt. Filippo moved to Lisbon and became a spice trader. Not suited for a desk job, he soon set sail seeking adventure in the orient. 

In a 1586 letter to his old friend Valori, Sassetti discusses an Indian remedy against the plague, with a substance called bezoar. The bezoar stone is a mass that develops and becomes trapped in the digestive systems of certain animals. It often resembles a smooth rock. Some thought ground bezoar to be a universal antidote to any poison. Sassetti was puzzled about how the grindings of bezoar could work to cure the plague. Its Aristotelian elemental properties would not be a match for correcting the imbalance of humors in the body. "This is a principle," he explains, taught to him by Neri Neri. "I have thought about it and I can not understand how it works, because the plague is of the same corruption and this is a lack of heat inherent in the humidity. And the stones, if I recall correctly, they have a cold and dry complexion, hence may not precede the restoration of heat. Messer Neri one time did me the favor of telling me." 

In another letter to Baccio Valori, Sassetti notes that he has collected rare varieties of cinnamon in his travels along the Malibar coast in India. His intention was to rediscover the species thought to be a powerful cure of disease by the ancients. He planned to send a parcel of seeds of these and other medicinal plants. "If it pleases God, in the coming year, I will send this to you, so that you may see it all, together with our Messer Neri Neri, who graces my memories." Later he writes that he is sending Baccio the discourse on cinnamon, which he has compiled, along with some plants. These, it later turned out, were water damaged in the journey. He had hoped for some help from Neri Neri on the question of whether the cinnamon he collected from the island of Zeilan [Ceylon], is the same thing as the curative cinnamon of Mantua described by the ancients. Valori was an authority on these matters in his own right. As librarian for the Medici's imposing collection of books and manuscripts, he had vast academic access. As keeper of the simples garden, he had first hand experience in horticulture and its derivative medicinal cures. 

The principles of "humorism" were passed down from celebrated physicians of the ancient world, like Galen, Hippocrates and Dioscorides. It was thought that the cure of disease was dependent on the restoration of balance between four substances in the body: blood, phlegm, black bile and yellow bile. In turn, each of these was associated with one of the Aristotelian elements: air, water, earth and fire respectively. Each was further associated with specific symptoms and characteristic traits of the patient, even their psychological outlook and physical complexion. This system formed the foundation of Western medicine and was taught and practiced well into the nineteenth century. Although, within Antonio Neri's lifetime newer experimentally based methods did start to take hold. A decade after his father's death, in a 1609 letter, Antonio boasts about his success in curing disease in Antwerp using the methods of the medical upstart Paracelsus. It is unlikely that his father would have approved.

*This post first appeared here 13 August 2014.

Filippo Sassetti

Goa, India 1509

Later distinguished as a renowned glassmaker and alchemist, Antonio Neri was born into a patrician household. In the Florentine baptism records, his entry was made on a Thursday, the first of March, 1576. He was born the previous evening, to Dianora Parenti and Neri Neri. His godmother is listed in the document as Ginevra Sassetti. Not a great amount is known about her; she was from a prominent family, at the time in her late fifties. However, there are indications that other members of her family interacted with the Neri's. Her nephew Filippo mentions Antonio's father favorably several times in letters, providing a fascinating glimpse into the way disease was diagnosed and treated.

When Antonio was born, his father Neri Neri was in his early thirties, and already a highly regarded physician. Baccio Valori was director of the famed Laurentian Library in Florence and steward of the Medici's simples (medicinal herbs) garden. He was friend to Neri Neri and godfather to Antonio's oldest sister Lessandra. Between 1583 and 1588, Valori received letters from a mutual friend, Filippo Sassetti, who was living in Goa and Cochin – trading settlements in India. Filippo was a native Florentine; he attended university in Pisa with Valori and they became lifelong friends. After Sassetti's father was forced to sell the family home to pay off a debt. Filippo moved to Lisbon and became a spice trader. Not suited for a desk job, he soon set sail seeking adventure in the orient. 

In a 1586 letter to his old friend Valori, Sassetti discusses an Indian remedy against the plague, with a substance called bezoar. The bezoar stone is a mass that develops and becomes trapped in the digestive systems of certain animals. It often resembles a smooth rock. Some thought ground bezoar to be a universal antidote to any poison. Sassetti was puzzled about how the grindings of bezoar could work to cure the plague. Its Aristotelian elemental properties would not be a match for correcting the imbalance of humors in the body. "This is a principle," he explains, taught to him by Neri Neri. "I have thought about it and I can not understand how it works, because the plague is of the same corruption and this is a lack of heat inherent in the humidity. And the stones, if I recall correctly, they have a cold and dry complexion, hence may not precede the restoration of heat. Messer Neri one time did me the favor of telling me." 

In another letter to Baccio Valori, Sassetti notes that he has collected rare varieties of cinnamon in his travels along the Malibar coast in India. His intention was to rediscover the species thought to be a powerful cure of disease by the ancients. He planned to send a parcel of seeds of these and other medicinal plants. "If it pleases God, in the coming year, I will send this to you, so that you may see it all, together with our Messer Neri Neri, who graces my memories." Later he writes that he is sending Baccio the discourse on cinnamon, which he has compiled, along with some plants. These, it later turned out, were water damaged in the journey. He had hoped for some help from Neri Neri on the question of whether the cinnamon he collected from the island of Zeilan [Ceylon], is the same thing as the curative cinnamon of Mantua described by the ancients. Valori was an authority on these matters in his own right. As librarian for the Medici's imposing collection of books and manuscripts, he had vast academic access. As keeper of the simples garden, he had first hand experience in horticulture and its derivative medicinal cures. 

The principles of "humorism" were passed down from celebrated physicians of the ancient world, like Galen, Hippocrates and Dioscorides. It was thought that the cure of disease was dependent on the restoration of balance between four substances in the body: blood, phlegm, black bile and yellow bile. In turn, each of these was associated with one of the Aristotelian elements: air, water, earth and fire respectively. Each was further associated with specific symptoms and characteristic traits of the patient, even their psychological outlook and physical complexion. This system formed the foundation of Western medicine and was taught and practiced well into the nineteenth century. Although, within Antonio Neri's lifetime newer experimentally based methods did start to take hold. A decade after his father's death, in a 1609 letter, Antonio boasts about his success in curing disease in Antwerp using the methods of the medical upstart Paracelsus. It is unlikely that his father would have approved.

*This post first appeared here 13 August 2014.

Filippo Sassetti

Goa, India 1509

Later distinguished as a renowned glassmaker and alchemist, Antonio Neri was born into a patrician household. In the Florentine baptism records, his entry was made on a Thursday, the first of March, 1576. He was born the previous evening, to Dianora Parenti and Neri Neri. His godmother is listed in the document as Ginevra Sassetti. Not a great amount is known about her; she was from a prominent family, at the time in her late fifties. However, there are indications that other members of her family interacted with the Neri's. Her nephew Filippo mentions Antonio's father favorably several times in letters, providing a fascinating glimpse into the way disease was diagnosed and treated.

When Antonio was born, his father Neri Neri was in his early thirties, and already a highly regarded physician. Baccio Valori was director of the famed Laurentian Library in Florence and steward of the Medici's simples (medicinal herbs) garden. He was friend to Neri Neri and godfather to Antonio's oldest sister Lessandra. Between 1583 and 1588, Valori received letters from a mutual friend, Filippo Sassetti, who was living in Goa and Cochin – trading settlements in India. Filippo was a native Florentine; he attended university in Pisa with Valori and they became lifelong friends. After Sassetti's father was forced to sell the family home to pay off a debt. Filippo moved to Lisbon and became a spice trader. Not suited for a desk job, he soon set sail seeking adventure in the orient. 

In a 1586 letter to his old friend Valori, Sassetti discusses an Indian remedy against the plague, with a substance called bezoar. The bezoar stone is a mass that develops and becomes trapped in the digestive systems of certain animals. It often resembles a smooth rock. Some thought ground bezoar to be a universal antidote to any poison. Sassetti was puzzled about how the grindings of bezoar could work to cure the plague. Its Aristotelian elemental properties would not be a match for correcting the imbalance of humors in the body. "This is a principle," he explains, taught to him by Neri Neri. "I have thought about it and I can not understand how it works, because the plague is of the same corruption and this is a lack of heat inherent in the humidity. And the stones, if I recall correctly, they have a cold and dry complexion, hence may not precede the restoration of heat. Messer Neri one time did me the favor of telling me." 

In another letter to Baccio Valori, Sassetti notes that he has collected rare varieties of cinnamon in his travels along the Malibar coast in India. His intention was to rediscover the species thought to be a powerful cure of disease by the ancients. He planned to send a parcel of seeds of these and other medicinal plants. "If it pleases God, in the coming year, I will send this to you, so that you may see it all, together with our Messer Neri Neri, who graces my memories." Later he writes that he is sending Baccio the discourse on cinnamon, which he has compiled, along with some plants. These, it later turned out, were water damaged in the journey. He had hoped for some help from Neri Neri on the question of whether the cinnamon he collected from the island of Zeilan [Ceylon], is the same thing as the curative cinnamon of Mantua described by the ancients. Valori was an authority on these matters in his own right. As librarian for the Medici's imposing collection of books and manuscripts, he had vast academic access. As keeper of the simples garden, he had first hand experience in horticulture and its derivative medicinal cures. 

The principles of "humorism" were passed down from celebrated physicians of the ancient world, like Galen, Hippocrates and Dioscorides. It was thought that the cure of disease was dependent on the restoration of balance between four substances in the body: blood, phlegm, black bile and yellow bile. In turn, each of these was associated with one of the Aristotelian elements: air, water, earth and fire respectively. Each was further associated with specific symptoms and characteristic traits of the patient, even their psychological outlook and physical complexion. This system formed the foundation of Western medicine and was taught and practiced well into the nineteenth century. Although, within Antonio Neri's lifetime newer experimentally based methods did start to take hold. A decade after his father's death, in a 1609 letter, Antonio boasts about his success in curing disease in Antwerp using the methods of the medical upstart Paracelsus. It is unlikely that his father would have approved.

*This post first appeared here 13 August 2014.

Filippo Sassetti

Goa, India 1509

Later distinguished as a renowned glassmaker and alchemist, Antonio Neri was born into a patrician household. In the Florentine baptism records, his entry was made on a Thursday, the first of March, 1576. He was born the previous evening, to Dianora Parenti and Neri Neri. His godmother is listed in the document as Ginevra Sassetti. Not a great amount is known about her; she was from a prominent family, at the time in her late fifties. However, there are indications that other members of her family interacted with the Neri's. Her nephew Filippo mentions Antonio's father favorably several times in letters, providing a fascinating glimpse into the way disease was diagnosed and treated.

When Antonio was born, his father Neri Neri was in his early thirties, and already a highly regarded physician. Baccio Valori was director of the famed Laurentian Library in Florence and steward of the Medici's simples (medicinal herbs) garden. He was friend to Neri Neri and godfather to Antonio's oldest sister Lessandra. Between 1583 and 1588, Valori received letters from a mutual friend, Filippo Sassetti, who was living in Goa and Cochin – trading settlements in India. Filippo was a native Florentine; he attended university in Pisa with Valori and they became lifelong friends. After Sassetti's father was forced to sell the family home to pay off a debt. Filippo moved to Lisbon and became a spice trader. Not suited for a desk job, he soon set sail seeking adventure in the orient. 

In a 1586 letter to his old friend Valori, Sassetti discusses an Indian remedy against the plague, with a substance called bezoar. The bezoar stone is a mass that develops and becomes trapped in the digestive systems of certain animals. It often resembles a smooth rock. Some thought ground bezoar to be a universal antidote to any poison. Sassetti was puzzled about how the grindings of bezoar could work to cure the plague. Its Aristotelian elemental properties would not be a match for correcting the imbalance of humors in the body. "This is a principle," he explains, taught to him by Neri Neri. "I have thought about it and I can not understand how it works, because the plague is of the same corruption and this is a lack of heat inherent in the humidity. And the stones, if I recall correctly, they have a cold and dry complexion, hence may not precede the restoration of heat. Messer Neri one time did me the favor of telling me." 

In another letter to Baccio Valori, Sassetti notes that he has collected rare varieties of cinnamon in his travels along the Malibar coast in India. His intention was to rediscover the species thought to be a powerful cure of disease by the ancients. He planned to send a parcel of seeds of these and other medicinal plants. "If it pleases God, in the coming year, I will send this to you, so that you may see it all, together with our Messer Neri Neri, who graces my memories." Later he writes that he is sending Baccio the discourse on cinnamon, which he has compiled, along with some plants. These, it later turned out, were water damaged in the journey. He had hoped for some help from Neri Neri on the question of whether the cinnamon he collected from the island of Zeilan [Ceylon], is the same thing as the curative cinnamon of Mantua described by the ancients. Valori was an authority on these matters in his own right. As librarian for the Medici's imposing collection of books and manuscripts, he had vast academic access. As keeper of the simples garden, he had first hand experience in horticulture and its derivative medicinal cures. 

The principles of "humorism" were passed down from celebrated physicians of the ancient world, like Galen, Hippocrates and Dioscorides. It was thought that the cure of disease was dependent on the restoration of balance between four substances in the body: blood, phlegm, black bile and yellow bile. In turn, each of these was associated with one of the Aristotelian elements: air, water, earth and fire respectively. Each was further associated with specific symptoms and characteristic traits of the patient, even their psychological outlook and physical complexion. This system formed the foundation of Western medicine and was taught and practiced well into the nineteenth century. Although, within Antonio Neri's lifetime newer experimentally based methods did start to take hold. A decade after his father's death, in a 1609 letter, Antonio boasts about his success in curing disease in Antwerp using the methods of the medical upstart Paracelsus. It is unlikely that his father would have approved.

*This post first appeared here 13 August 2014.

Filippo Sassetti

Goa, India 1509

In the Florentine baptism records, the entry for Antonio Neri was made on a Thursday, the first of March, 1576. He was born the previous evening, to Dianora Parenti and Neri Neri. His godmother is listed in the document as Ginevra Sassetti. Not a great amount is known about her; she was from a prominent family, at the time in her late fifties. However, there are indications that other members of her family interacted with the Neri's. Her nephew Filippo mentions Antonio's father favorably several times in letters, providing a fascinating glimpse into the way disease was diagnosed and treated.

When Antonio was born, his father Neri Neri was in his early thirties, and already a highly regarded physician. Baccio Valori was director of the famed Laurentian Library in Florence and steward of the Medici's simples (medicinal herbs) garden. He was friend to Neri Neri and godfather to Antonio's oldest sister Lessandra. Between 1583 and 1588, Valori received letters from a mutual friend, Filippo Sassetti, who was living in Goa and Cochin – trading settlements in India. Filippo was a native Florentine; he attended university in Pisa with Valori and they became lifelong friends. After Sassetti's father was forced to sell the family home to pay off a debt. Filippo moved to Lisbon and became a spice trader. Not suited for a desk job, he soon set sail seeking adventure in the orient. 

In a 1586 letter to his old friend Valori, Sassetti discusses an Indian remedy against the plague, with a substance called bezoar. The bezoar stone is a mass that develops and becomes trapped in the digestive systems of certain animals. It often resembles a smooth rock. Some thought ground bezoar to be a universal antidote to any poison. Sassetti was puzzled about how the grindings of bezoar could work to cure the plague. Its Aristotelian elemental properties would not be a match for correcting the imbalance of humors in the body. "This is a principle," he explains, taught to him by Neri Neri. "I have thought about it and I can not understand how it works, because the plague is of the same corruption and this is a lack of heat inherent in the humidity. And the stones, if I recall correctly, they have a cold and dry complexion, hence may not precede the restoration of heat. Messer Neri one time did me the favor of telling me." 

In another letter to Baccio Valori, Sassetti notes that he has collected rare varieties of cinnamon in his travels along the Malibar coast in India. His intention was to rediscover the species thought to be a powerful cure of disease by the ancients. He planned to send a parcel of seeds of these and other medicinal plants. "If it pleases God, in the coming year, I will send this to you, so that you may see it all, together with our Messer Neri Neri, who graces my memories." Later he writes that he is sending Baccio the discourse on cinnamon, which he has compiled, along with some plants. These, it later turned out, were water damaged in the journey. He had hoped for some help from Neri Neri on the question of whether the cinnamon he collected from the island of Zeilan [Ceylon], is the same thing as the curative cinnamon of Mantua described by the ancients. Valori was an authority on these matters in his own right. As librarian for the Medici's imposing collection of books and manuscripts, he had vast academic access. As keeper of the simples garden, he had first hand experience in horticulture and its derivative medicinal cures. 

The principles of "humorism" were passed down from celebrated physicians of the ancient world, like Galen, Hippocrates and Dioscorides. It was thought that the cure of disease was dependent on the restoration of balance between four substances in the body: blood, phlegm, black bile and yellow bile. In turn, each of these was associated with one of the Aristotelian elements: air, water, earth and fire respectively. Each was further associated with specific symptoms and characteristic traits of the patient, even their psychological outlook and physical complexion. This system formed the foundation of Western medicine and was taught and practiced well into the nineteenth century. Although, within Antonio Neri's lifetime newer experimentally based methods did start to take hold. A decade after his father's death, in a 1609 letter, Antonio boasts about his success in curing disease in Antwerp using the methods of the medical upstart Paracelsus. It is unlikely that his father would have approved.

*This post first appeared here 13 August 2014.

Filippo Sassetti

Goa, India 1509

In the Florentine baptism records, the entry for Antonio Neri was made on a Thursday, the first of March, 1576. He was born the previous evening, to Dianora Parenti and Neri Neri. His godmother is listed in the document as Ginevra Sassetti. Not a great amount is known about her; she was from a prominent family, at the time in her late fifties. However, there are indications that other members of her family interacted with the Neri's. Her nephew Filippo mentions Antonio's father favorably several times in letters, providing a fascinating glimpse into the way disease was diagnosed and treated.

When Antonio was born, Neri Neri was in his early thirties, and already a highly regarded physician. Baccio Valori was director of the famed Laurentian Library in Florence and steward of the Medici's simples (medicinal herbs) garden. He was friend to Neri Neri and godfather to Antonio's oldest sister Lessandra. Between 1583 and 1588, Valori received letters from a mutual friend, Filippo Sassetti, who was living in Goa and Cochin – trading settlements in India. Filippo was a native Florentine; he attended university in Pisa with Valori and they became lifelong friends. After Sassetti's father was forced to sell the family home to pay off a debt. Filippo moved to Lisbon and became a spice trader. Not suited for a desk job, he soon set sail seeking adventure in the orient. 

In a 1586 letter to his old friend Valori, Sassetti discusses an Indian remedy against the plague, with a substance called bezoar. The bezoar stone is a mass that develops and becomes trapped in the digestive systems of certain animals. It often resembles a smooth rock. Some thought ground bezoar to be a universal antidote to any poison. Sassetti was puzzled about how the grindings of bezoar could work to cure the plague. Its Aristotelian elemental properties would not be a match for correcting the imbalance of humors in the body. "This is a principle," he explains, taught to him by Neri Neri. "I have thought about it and I can not understand how it works, because the plague is of the same corruption and this is a lack of heat inherent in the humidity. And the stones, if I recall correctly, they have a cold and dry complexion, hence may not precede the restoration of heat. Messer Neri one time did me the favor of telling me." 

In another letter to Baccio Valori, Sassetti notes that he has collected rare varieties of cinnamon in his travels along the Malibar coast in India. His intention was to rediscover the species thought to be a powerful cure of disease by the ancients. He planned to send a parcel of seeds of these and other medicinal plants. "If it pleases God, in the coming year, I will send this to you, so that you may see it all, together with our Messer Neri Neri, who graces my memories." Later he writes that he is sending Baccio the discourse on cinnamon, which he has compiled, along with some plants. These, it later turned out, were water damaged in the journey. He had hoped for some help from Neri Neri on the question of whether the cinnamon he collected from the island of Zeilan [Ceylon], is the same thing as the curative cinnamon of Mantua described by the ancients. Valori was an authority on these matters in his own right. As librarian for the Medici's imposing collection of books and manuscripts, he had vast academic access. As keeper of the simples garden, he had first hand experience in horticulture and its derivative medicinal cures. 

The principles of "humorism" were passed down from celebrated physicians of the ancient world, like Galen, Hippocrates and Dioscorides. It was thought that the cure of disease was dependent on the restoration of balance between four substances in the body: blood, phlegm, black bile and yellow bile. In turn, each of these was associated with one of the Aristotelian elements: air, water, earth and fire respectively. Each was further associated with specific symptoms and characteristic traits of the patient, even their psychological outlook and physical complexion. This system formed the foundation of Western medicine and was taught and practiced well into the nineteenth century. Although, within Antonio Neri's lifetime newer experimentally based methods did start to take hold. A decade after his father's death, in a 1609 letter, Antonio boasts about his success in curing disease in Antwerp using the methods of the medical upstart Paracelsus. It is unlikely that his father would have approved.

*This post first appeared here 13 August 2014.

Donato Altomare

Donato Altomare, engr. C. Biendi,  from

 "Biografia degli uomini illustri del regno di Napoli,"

In sixteenth century Europe, it was not easy being a physician if your philosophy of medicine deviated from the norm. In those days, the 'norm' was to treat all diseases solely based on elementary properties or "humors" as they were called. Successful treatment, according to theory, depended on the restoration of balance between the four humors which were in turn associated with air, water, earth and fire. For example, symptoms that included a burning fever called for a diametrically opposite treatment than for a patient with chills. Sometimes these procedures worked, other times not so much. These principles were very old; they had been established centuries earlier in the writings of Hippocrates and Galen and the wisdom of the ancients was not generally questioned. The medical establishment was locked into these concepts and to deviate was to risk severe criticism from one’s professional peers. 

An early maverick was one-time mining physician Paracelsus. Today he is known as a pioneer of sorts; he focused his attention on practical solutions that worked in the field rather than on dogmatic theories. He insisted on basing his treatment, not blindly on a set of rules, but on close observation of his patients and of nature. Increasingly, his peers considered him a dangerous crackpot and a liability for his unorthodox treatments. He spent the last part of his life running from one town to another, trying desperately to stay ahead of his detractors. The fact that he was also outspoken about his belief of an impending apocalypse did not help his case. He died in 1541 and his ideas about chemistry and medicine did not start to gain traction until about fifty years later, when among many others, alchemists Antonio Neri and his sponsor Prince Don Antonio de' Medici became devotees.

Paracelsus is an extreme example, and perhaps the best known, but he was far from alone in a rising tide of debate about the nature of disease. A much lesser known example, one that peripherally involved Neri's own father was that of Neapolitan physician Donato Altomare who was a university professor in the middle of the sixteenth century. He was hounded out of Naples and forced to relocate in Rome after favoring the opinions of leading Arab physicians over established theory, but philosophically, he was still very much in the mainstream of promoting the ideas of Galen and Hippocrates. The old ideology was held so tightly, that even a slight deviation could leave a career in ruins. Ultimately, Altomare found favor with fellow Neapolitan Pope Paul IV, rehabilitated his reputation and was allowed to return to his hometown, but criticism persisted. One of his most vocal detractors was a classmate of his own son, named Salvo Sclano. 

In 1585, a book on a variety of topics in medical theory was published by one of the leading doctors, Antonio Alvarez, personal physician to the Viceroy of Naples. In Epistolarum et Consiliorum Medicinalium pars prima, Alvarez invited a number of well-respected peers to contribute chapters in the form of letters. The book is most noted for the final chapter in which Alvarez mounts a spirited defense of the above-mentioned Donato Altomare and against his nemesis Sclano.

Antonio Neri's father, Neri Neri, has a detailed chapter in Alvarez's book. The elder Neri was the personal physician to the grand duke of Tuscany, Ferdinando de' Medici. In his piece, he wrote on the treatment of what was known as "left side paralysis," usually the result of a stroke, which often left patients physically debilitated and unable to speak. This same malady befell a close Neri family friend in the 1560's. Poet and historian Lodovico Domenichi spent the end of his life unable to speak, but still attended by his best friend, Antonio's grandfather, Jacopo Neri. The medical problem was correctly identified as originating in the brain, but the prescribed treatment was, shall we say, less than optimal. An incision was made in the rear of the patient's head at the base of the skull. Wires or small beads were inserted to keep the wound open. The theory was that deep pathogens were drawn out of the body, as evidenced by the large discharge of puss that resulted. 

The fact that Neri Neri contributed to the book is an indication that he was in sympathy with Alvarez's defense of Altomare. It is interesting that while he was quietly championing the minor revision of  main-stream Galenic medicine, his son Antonio would go on to champion the far more radical teachings of Paracelsus. While the majority of Antonio's writings deal with medical cures, nowhere does he discuss the theory of "humors" or Galenic medicine, although he also does not speak out against it. In his own quiet way, Antonio Neri was helping to sever ties to the old ways of medical practice. In the future, the emphasis of medical science would be squarely focused on careful observation of nature.

*  This post first appeared here as "Physician Steel Thyself" on 30 July 2014. 

Filippo Sassetti

Goa, India 1509

In the Florentine baptism records, the entry for Antonio Neri was made on a Thursday, the first of March, 1576. He was born the previous evening, to Dianora Parenti and Neri Neri. His godmother is listed in the document as Ginevra Sassetti. Not a great amount is known about her; she was from a prominent family, at the time in her late fifties. However, there are indications that other members of her family interacted with the Neri's. Her nephew Filippo mentions Antonio's father favorably several times in letters, providing a fascinating glimpse into the way disease was diagnosed and treated.

When Antonio was born, Neri Neri was in his early thirties, and already a highly regarded physician. Baccio Valori was director of the famed Laurentian Library in Florence and steward of the Medici's simples (medicinal herbs) garden. He was friend to Neri Neri and godfather to Antonio's oldest sister Lessandra. Between 1583 and 1588, Valori received letters from a mutual friend, Filippo Sassetti, who was living in Goa and Cochin – trading settlements in India. Filippo was a native Florentine; he attended university in Pisa with Valori and they became lifelong friends. After Sassetti's father was forced to sell the family home to pay off a debt. Filippo moved to Lisbon and became a spice trader. Not suited for a desk job, he soon set sail seeking adventure in the orient. 

In a 1586 letter to his old friend, Sassetti discusses an Indian remedy against the plague, with a substance called bezoar. The bezoar stone is a mass that develops and becomes trapped in the digestive systems of certain animals. It often resembles a smooth rock. Some thought ground bezoar to be a universal antidote to any poison. Sassetti was puzzled about how the grindings of bezoar could work to cure the plague. Its Aristotelian elemental properties would not be a match for correcting the imbalance of humors in the body. This is a principle, he explains, taught to him by Neri Neri. "I have thought about it and I can not understand how it works, because the plague is of the same corruption and this is a lack of heat inherent in the humidity. And the stones, if I recall correctly, they have a cold and dry complexion, hence may not precede the restoration of heat. Messer Neri one time did me the favor of telling me." 

In another letter to Baccio Valori, Sassetti notes that he has collected rare varieties of cinnamon in his travels along the Malibar coast in India. His intention was to rediscover the species thought to be a powerful cure of disease by the ancients. He planned to send a parcel of seeds of these and other medicinal plants. "If it pleases God, in the coming year, I will send this to you, so that you may see it all, together with our Messer Neri Neri, who graces my memories." Later he writes that he is sending Baccio the discourse on cinnamon, which he has compiled, along with some plants. These, it later turned out, were water damaged in the journey. He had hoped for some help from Neri Neri on the question of whether the cinnamon he collected from the island of Zeilan [Ceylon], is the same thing as the curative cinnamon of Mantua described by the ancients. Valori was an authority on these matters in his own right. As librarian for the Medici's imposing collection of books and manuscripts, he had vast academic access. As keeper of the simples garden, he had first hand experience in horticulture and its derivative medicinal cures. 

The principles of "humorism" were passed down from celebrated physicians of the ancient world, like Galen and Hippocrates. It was thought that the cure of disease was dependent on the restoration of balance between four substances in the body: blood, phlegm, black bile and yellow bile. In turn, each of these was associated with one of the Aristotelian elements: air, water, earth and fire respectively. Each was further associated with specific symptoms and characteristic traits of the patient, even their psychological outlook and physical complexion. This system formed the foundation of Western medicine and was taught and practiced well into the nineteenth century. Although, within Antonio Neri's lifetime newer experimentally based methods did start to take hold. A decade after his father's death, in a 1609 letter, Antonio boasts about his success in curing disease in Antwerp using the methods of the medical upstart Paracelsus. It is unlikely that his father would have approved.

Physician 'Steel' Thyself

Donato Altomare, engr. C. Biendi,  from
 "Biografia degli uomini illustri del regno di Napoli,"

In sixteenth century Europe, it was not easy being a physician if your philosophy of medicine deviated from the norm. In those days, the 'norm' was to treat all diseases solely based on elementary properties or "humors" as they were called. Successful treatment, according to theory, depended on the restoration of balance between the four humors which were in turn associated with air, water, earth and fire. For example, symptoms including a burning fever called for the diametrically opposite treatment from chills. Sometimes these procedures worked, other times not so much. These principles were very old; they had been established centuries earlier in the writings of Hippocrates and Galen and the wisdom of the ancients was not generally questioned. The medical establishment was locked into these concepts and to deviate was to risk severe criticism from one’s professional peers. 

An early maverick was one-time mining physician Paracelsus. Today he is known as a pioneer of sorts; he focused his attention on practical solutions that worked in the field rather than on dogmatic theories. He insisted on basing his treatment, not blindly on a set of rules, but on close observation of his patients and of nature. Increasingly, his peers considered him a dangerous crackpot and a liability for his unorthodox treatments. He spent the last part of his life running from one town to another, trying desperately to stay ahead of his detractors. The fact that he was also outspoken about his belief of an impending apocalypse did not help his case. He died in 1541 and his ideas about chemistry and medicine did not start to gain traction until about fifty years later, when among others, alchemists Antonio Neri and his sponsor Prince Don Antonio de' Medici became devotees.

Paracelsus is an extreme example, and perhaps the best known, but he was far from alone in a rising tide of debate about the nature of disease. A much lesser known example, one that peripherally involved Neri's own father was that of Neapolitan physician Donato Altomare who was a university professor in the middle of the sixteenth century. He was hounded out of Naples and forced to relocate in Rome after favoring the opinions of leading Arab physicians over established theory, but philosophically, he was still very much in the mainstream of promoting the ideas of Galen and Hippocrates. The old ideology was held so tightly, that even a slight deviation could leave a career in ruins. Ultimately, Altomare found favor with fellow Neapolitan Pope Paul IV, rehabilitated his reputation and was allowed to return to his hometown, but criticism persisted. One of his most vocal detractors was a classmate of his own son, named Salvo Sclano. 

In 1585, a book on a variety of topics in medical theory was published by one of the leading doctors, Antonio Alvarez, personal physician to the Viceroy of Naples. In Epistolarum et Consiliorum Medicinalium pars prima, he invited a number of well-respected peers to contribute chapters in the form of letters. The book is most noted for the final chapter in which Alvarez mounts a spirited defense of the above-mentioned Donato Altomare and against his nemesis Sclano.

Antonio Neri's father has a detailed chapter in Alvarez's book. Neri Neri was the personal physician to the grand duke of Tuscany, Ferdinando de' Medici. In his piece, he wrote on the treatment of what was known as "left side paralysis," usually the result of a stroke, which often left patients physically debilitated and unable to speak. This same malady befell a close Neri family friend in the 1560's. Poet and historian Lodovico Domenichi spent the end of his life unable to speak, but still attended by his best friend, Antonio's grandfather, Jacopo Neri. The medical problem was correctly identified as originating in the brain, but the prescribed treatment was, shall we say, less than optimal by current standards. An incision was made in the rear of the patient's head at the base of the skull. Wires or small beads were inserted to keep the wound open. The theory was that deep pathogens were drawn out of the body, as evidenced by the large discharge of puss that resulted. 

The fact that Neri Neri contributed to the book is an indication that he was in sympathy with Alvarez's defense of Altomare. It is interesting that while he was quietly championing the minor revision of  main-stream Galenic medicine, his son Antonio would go on to champion the far more radical teachings of Paracelsus. While the majority of Antonio's writings deal with medical cures, nowhere does he discuss the theory of "humors" or Galenic medicine, although he also does not speak out against it. In his own quiet way, Antonio Neri was helping to sever ties to the old ways of medical practice. In the future, the emphasis of medical science would be squarely focused on careful observation of nature.